面肌痉挛和局限性肌张力障碍在神经科并非少见,对于病程长、痉挛严重及多种治疗方法无效患者的治疗,以往是神经科的一大难题。1979年Scott等[1]首次应用A型肉毒毒素(botulium toxin A,BTX-A)治疗斜视成功后,以后逐渐应用于眼睑痉挛、面肌痉挛和痉挛性斜颈等治疗,被认为是近年神 Hemifacial spasm and focal dystonia are not uncommon in neurology. In the past, the treatment of patients with long duration, severe spasticity, and ineffective treatment methods was a major neurological challenge. In 1979 Scott et al [1] first botulinum toxin A (BTX-A) treatment of strabismus success, and later gradually applied to blepharospasm, hemifacial spasm and spasmodic torticollis and other treatment is considered in recent years God