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二烯丙基二硫(diallyl disulfide,DADS)是大蒜主要有效成分烯丙基硫化物中的一类低分子量脂溶性化合物,可通过多种途径起到抗肿瘤作用。近年来,DADS的抗癌作用受到国内外广泛关注,并且其抗癌机制的研究已经进入细胞、分子水平。现就DADS抗肿瘤的作用机制作一综述。
Diallyl disulfide (DADS) is a kind of low molecular weight fat-soluble compound in allyl sulfide, which is the main active ingredient in garlic. It can exert anti-tumor effect through a variety of ways. In recent years, the anticancer effect of DADS has drawn wide attention both at home and abroad, and the research on its anticancer mechanism has entered the cell and molecular level. The mechanism of anti-tumor effect of DADS is reviewed.