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目的了解湖州市新确证的男男性行为人群HIV/AIDS患者首次CD4~+T淋巴细胞水平及相关情况,为早期开展抗病毒治疗和现场干预提供依据。方法采用流式细胞仪对新确证的207例男男性行为人群HIV/AIDS患者进行首次CD4~+T淋巴细胞绝对值计数,统计分析其测定值。结果 207例患者中,CD4~+T淋巴细胞数最少为25个/μl,最多为1 006个/μl,平均(419.1±245.4)个/μl。其中≤200个/μl 38例,占18.4%(38/207);201个/μl~350个/μl 62例,占30.0%(62/207)。不同年龄、婚姻状况、文化程度男男性行为人群HIV/AIDS患者CD4~+T淋巴细胞结果比较,差异无统计学意义(P>0.05)。结论湖州市男男性行为人群HIV/AIDS患者首次CD4~+T淋巴细胞水平相对偏低,应加强对男男性行为人群艾滋病相关知识宣传,使更多的HIV感染者和发生高危行为的人尽早到相关医疗单位进行咨询检测,以便及早发现和提高早期抗病毒治疗的机会。
Objective To understand the level of CD4 ~ + T lymphocytes in HIV / AIDS patients newly identified in MSM in Huzhou and provide the basis for antiviral therapy and intervention in the field. Methods Flow cytometry was used to count the first absolute CD4 ~ + T lymphocyte counts in 207 newly diagnosed MSM HIV / AIDS patients, and the results were statistically analyzed. Results Among the 207 patients, the number of CD4 ~ + T lymphocytes was at least 25 / μl, up to 1006 / μl, with an average of (419.1 ± 245.4) / μl. Among them, 38 cases were ≤200 / μl, accounting for 18.4% (38/207); 62 cases were 201 / μl ~ 350 / μl, accounting for 30.0% (62/207). The results of CD4 ~ + T lymphocyte in HIV / AIDS patients with different ages, marital status and educational level were not statistically different (P> 0.05). Conclusions The first CD4 ~ + T lymphocyte in HIV / AIDS patients in MSM population is relatively low in Huzhou City. HIV / AIDS-related knowledge should be promoted in MSM population, so that more HIV-infected persons and people with high-risk behaviors should be treated as soon as possible The relevant medical units conduct counseling and testing in order to detect and improve early detection of antiviral treatment.