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目的观察糖皮质激素治疗间质性肺病急重症的效果。方法将80例间质性肺病急重症患者。依据治疗的不同办法分为试验组27例与对照组53例。试验组采取常规方法联合糖皮质激素共同治疗,对照组采取常规方法治疗,未进行糖皮质激素的治疗。比较2组患者治疗1周后的CRP分数及血气水平。结果治疗前2组CRP各项评分比较差异无统计学意义(P>0.05)。治疗后,2组CRP评分均低于治疗前,且试验组低于对照组,差异均具有统计学意义(P<0.05)。2组血气指标水平比较差异无统计学意义(P>0.05)。结论糖皮质激素在治疗间质性肺病中效果十分明显,可以有效减慢间质性肺病的进一步发展,对患者的生活品质有良好的改进结果,在临床上值得大力推广和应用。
Objective To observe the effect of glucocorticoids in the treatment of severe acute interstitial lung disease. Methods 80 cases of interstitial lung disease patients with severe disease. According to the different treatment methods were divided into experimental group of 27 cases and control group of 53 cases. The experimental group with conventional methods combined with glucocorticoid treatment, the control group to take conventional treatment, no glucocorticoid treatment. CRP scores and blood gas levels were compared between two groups after one week of treatment. Results There was no significant difference in CRP scores between the two groups before treatment (P> 0.05). After treatment, CRP scores of two groups were lower than before treatment, and the experimental group was lower than the control group, the difference was statistically significant (P <0.05). There was no significant difference in blood gas level between the two groups (P> 0.05). Conclusion The effect of glucocorticoids in the treatment of interstitial lung disease is very obvious, which can effectively slow down the further development of interstitial lung disease and improve the quality of life of patients. It is worthy of great promotion and application in clinic.