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目的分析研究奥卡西平治疗儿童癫痫病的临床效果。方法选取许昌市妇幼保健院2013年4月—2014年5月的60例儿童癫痫病患者,A组30例实施奥卡西平治疗,B组30例在采取其他药物治疗未果的前提下再实施奥卡西平治疗,对两组患者进行临床分析。结果 A组的总有效率(80.00%)高于B组(66.67%)A组的癫痫次数明显较B少,P<0.01,具有统计学意义。两组患儿的不良反应主要有头晕、恶心、乏力、皮疹等,血常规、实验室检查、心电图等均无异常现象,偶见血钠下降、呼吸道感染等,两组比较,P>0.05,不具有统计学意义。结论奥卡西平治疗儿童癫痫病安全、有效,值得在临床上推广使用。
Objective To analyze the clinical effect of oxcarbazepine on children epilepsy. Methods Sixty children with epilepsy from April 2013 to May 2014 in Xuchang Maternal and Child Health Hospital were enrolled in this study. A group of 30 patients received oxcarbazepine treatment and another 30 patients of group B received oxcarbazepine treatment without any other drugs. Cardiopathy treatment, clinical analysis of two groups of patients. Results The total effective rate (80.00%) in group A was significantly higher than that in group B (66.67%). The number of epilepsy in group A was significantly lower than that in group B (P <0.01), which was statistically significant. Adverse reactions of the two groups were mainly dizziness, nausea, fatigue, skin rashes, blood tests, laboratory tests, electrocardiogram, etc. No abnormalities, occasionally decreased serum sodium, respiratory infections, the two groups, P> 0.05, Not statistically significant. Conclusion oxcarbazepine treatment of children with epilepsy is safe and effective, it is worth in the clinical promotion.