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目的总结滤器预处理后连续性血液净化(CBP)治疗急性呼吸窘迫综合征(ARDS)的临床疗效。方法应用CBP治疗ARDS,按是否进行滤器预处理,36例患者分为治疗组和对照组。观察各组滤器使用数量,APACHEⅡ评分下降10分、氧合指数(PaO2/FiO2)升至≥300、C反应蛋白(CRP)降至≤10.0 mg/L的时间。结果治疗组使用滤器数量少于对照组,APACHEⅡ评分、PaO2/FiO2、CRP恢复目标值时间短于对照组。结论滤器经过预处理者临床效果明显。
Objective To summarize the clinical effect of continuous preconditioning and continuous blood purification (CBP) on acute respiratory distress syndrome (ARDS). Methods CBP treatment of ARDS, according to whether the pretreatment filter, 36 patients were divided into treatment group and control group. The number of filters used in each group was observed. The APACHE II score decreased by 10 points, the PaO2 / FiO2 level increased to ≥300 and the CRP decreased to ≤10.0 mg / L. Results The number of filters used in the treatment group was less than that in the control group. The APACHEⅡscore, PaO2 / FiO2 and CRP recovery time were shorter than those in the control group. Conclusions The filter has obvious clinical effect after pretreatment.