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目的评价尼莫地平联合硫酸镁治疗上尿路结石的疗效。方法将62例上尿路结石病人随机分为两组,治疗组32例,对照组30例,对照组常规应用控制感染、多饮水、输液及止痛治疗,治疗组在此基础上加用尼莫地平片20mg,3次,口服,并应用0.9%生理盐水250ml加25%硫酸镁5ml静滴,日1次,疗程7日。结果治疗组在疗程内结石顺利排出的时间短于对照组(P<0.05),需转外科手术者治疗组4例,对照组6例,两组比较无统计学意义(P>0.05)。结论尼莫地平联合硫酸镁治疗有利于上尿路结石排出,值得进一步尝试。
Objective To evaluate the efficacy of nimodipine combined with magnesium sulfate in the treatment of upper urinary tract calculi. Methods Sixty-two patients with upper urinary tract calculi were randomly divided into two groups: treatment group (32 cases) and control group (30 cases). The control group was used routinely for infection control, drinking water, infusion and analgesia. On the basis of this, Plain tablets 20mg, 3 times, orally, and application 0.9% saline 250ml plus 25% magnesium sulfate 5ml intravenous infusion, day 1, treatment of 7 days. Results In the treatment group, the time for the smooth discharge of stones was shorter in the treatment group than in the control group (P <0.05). The patients in the operation group needed to be treated in 4 cases and the control group in 6 cases. There was no significant difference between the two groups (P> 0.05). Conclusion Nimodipine and magnesium sulfate treatment is conducive to the discharge of upper urinary tract stones, it is worth further attempts.