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目的观察分析长期小剂量罗红霉素对稳定期慢性阻塞性肺疾病(COPD)的临床价值。方法选取本院在2011年12月~2012年11月诊治的74例稳定期COPD门诊患者的临床资料进行研究分析,并随机将患者分为治疗组(37例)和对照组(37例),对比两组患者治疗效果。结果对比两组患者治疗前后各项指标变化状况,差异无统计学意义(P>0.05);治疗后,两组患者各项指标显著优于治疗前的,差异有统计学意义(P<0.05);组间对比,治疗后治疗组患者各项指标显著优于对照组患者的,差异有统计学意义(P<0.05);对比两组患者急性发作频率,差异有统计学意义(P<0.05)。结论长期小剂量罗红霉素对稳定期COPD疾病疗效显著,可有效改善患者临床症状,提高患者生活质量。
Objective To observe the clinical value of long-term low-dose roxithromycin in patients with stable chronic obstructive pulmonary disease (COPD). Methods The clinical data of 74 patients with stable COPD clinics diagnosed and treated in our hospital from December 2011 to November 2012 were selected and analyzed. Patients were randomly divided into treatment group (37 cases) and control group (37 cases) Compare the treatment effect of two groups of patients. Results After treatment, there was no significant difference in each index between the two groups before and after treatment (P> 0.05). After treatment, the indexes in both groups were significantly better than those before treatment (P <0.05) (P <0.05). Comparing the two groups, the indexes in the treatment group were significantly better than those in the control group (P <0.05). Comparing the two groups of patients with acute seizure frequency, the difference was statistically significant (P0.05) . Conclusion Long-term low-dose roxithromycin has a significant effect on stable COPD disease, which can effectively improve the clinical symptoms and improve the quality of life of patients.