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本文应用鲁米诺(Luminol)依赖的全血化学发光法检测36例冠心病患者外周血中性粒细胞化学发光,其中心绞痛发作组17例,心绞痛未发作组19例,同时检测正常对照组30例。结果表明,心绞痛发作组患者中性粒细胞化学发光本底、峰值、斜率和积分、吞噬指数均较心绞痛未发作组显著增高(P<0.01～0.05);与正常对照组相比,心绞痛发作组中性粒细胞化学发光本底、峰值、斜率、积分及吞噬指数均显著增高(P<0.01),而心绞痛未发作组除本底外,其余各参数与正常对照组相比均无差异。提示心绞痛发作期患者中性粒细胞产生氧自由基增多。
In this paper, chemiluminescence of luminol-dependent whole blood was used to detect the chemiluminescence of peripheral blood in 36 patients with coronary heart disease. There were 17 cases of angina pectoris and 19 cases of angina pectoris without seizure, meanwhile 30 cases of normal control group 30 example. The results showed that the chemiluminescence background, peak, slope, integral and phagocytic index of neutrophils in patients with angina pectoris were significantly higher than those without angina pectoris (P <0.01 ~ 0.05). Compared with normal control group, angina pectoris group Neutrophil chemiluminescence background, peak, slope, integral and phagocytic index were significantly increased (P <0.01), while the angina pectoris group without the background, the other parameters were no significant difference compared with the normal control group. Prompted the onset of angina patients with neutrophils produce oxygen free radicals increased.