颅脑损伤是临床上复杂又严重的创伤性疾病,随着现代交通业与工业的发展,我国颅脑损伤的发病率也越来越高~([1-2])。尤其是中重度颅脑损伤[格拉斯哥昏迷指数(Glasgow Coma Scale,GCS)<8分]的致残率及病死率居高不下~([3-4])。同时多数ICU中重度颅脑损伤患者伴有头皮挫裂伤、颅骨骨折及脑组织挫裂伤、出血等症状,亦会出现头痛、呕吐,甚至昏迷等一系列颅内压增高症候群,影响患者疾病进展情况的观察和处 Brain injury is clinically complex and serious traumatic disease, with the development of modern transportation and industry, the incidence of craniocerebral injury in China is also getting higher and higher ~ ([1-2]). In particular, moderate to severe traumatic brain injury [Glasgow Coma Scale (GCS) <8 points] leads to high morbidity and mortality (3-4). At the same time, most ICU patients with severe craniocerebral injury accompanied by scalp laceration, skull fracture and brain tissue contusion, bleeding and other symptoms, headache, vomiting, and even coma and a series of intracranial hypertension syndrome affect the patient’s disease Observation and progress of progress