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本文观察了吲达帕胺治疗28例Ⅰ、Ⅱ期高血压患者的降压效果及其对血清电解质、血脂和脂质过氧化物的影响。结果表明:降压效果非常显著(P<0.01);对血清K~+、Na~+、Cl~-、Ca~(z+)的影响甚微(P>0.05);血TC和TG明显降低(P<0.01),而HDL-ch则升高(P<0.05);脂质过氧化物降低(P<0.05)。提示该药为较好的抗高血压一线药物。
This article investigates the antihypertensive effect of indapamide in 28 patients with stage I and II hypertension and its effects on serum electrolytes, lipids and lipid peroxides. The results showed that the antihypertensive effect was very significant (P <0.01), but had little effect on serum K +, Na +, Cl ~ - and Ca ~ (z +) (P> 0.05) P <0.01), while HDL-ch increased (P <0.05) and lipid peroxides decreased (P <0.05). Tip of the drug for better anti-hypertensive first-line drugs.