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目的 :评价雾化吸入沙丁胺醇及布地奈德联合治疗支气管哮喘急性发作的临床疗效。方法 :选取在我院就诊的支气管哮喘急性发作患者共74例,将其随机分为两组,其中观察组37例,采用雾化吸入沙丁胺醇及布地奈德进行联合治疗,对照组37例,采用沙丁胺醇雾化吸入治疗,观察并比较两组患儿临床疗效、1秒最大呼吸量(FEV1)、用力肺活量(FVC)、肺活量(VC)等指标。结果:治疗后观察组临床疗效以及各项指标均明显优于对照组,比较差异有统计学意义(P<0.05)。结论 :雾化吸入沙丁胺醇及布地奈德治疗支气管哮喘急性发作,在缓解症状,改善患者肺功能方面有较为优异的表现,值得在临床上予以推广。
Objective: To evaluate the clinical efficacy of inhaled salbutamol and budesonide in the treatment of acute exacerbation of bronchial asthma. Methods: A total of 74 patients with acute exacerbation of bronchial asthma were selected in our hospital. They were randomly divided into two groups, of which 37 patients in the observation group were treated with inhalation of salbutamol and budesonide. The control group received 37 Salbutamol inhalation therapy was used to observe and compare clinical curative effect, FEV1, FVC and VC of two groups. Results: After treatment, the clinical curative effect and each index of the observation group were obviously better than the control group, the difference was statistically significant (P <0.05). Conclusions: Nebulization of salbutamol and budesonide in the treatment of acute exacerbation of bronchial asthma has good performance in alleviating symptoms and improving lung function of patients, and it is worth to be popularized clinically.