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氨苄西林钠是临床广泛选用的广谱抗生素,而甲硝唑注射液因其价格较低,是同等剂量替硝唑针的1/3～1/2,疗效确切,是目前抗厌氧菌感染的首选药品。二者合用,特别适用于外科、妇产科的深部感染患者。但目前供临床参考使用的《256种注射液配伍变化检索表》却标明两者属配伍禁忌,给临床使用带来不便。本文通过对两者药剂学配伍后,不同时间段的含量及pH值测定,考察两者药剂学配伍的可行性。
Ampicillin sodium is a broad-spectrum antibiotics widely used clinically, and metronidazole injection because of its lower price, is the same dose of tinidazole needle 1/3 ~ 1/2, the exact effect, is currently the preferred drug against anaerobic infections . The combination of the two, especially for surgery, obstetrics and gynecology deep infection patients. However, for the clinical reference to use the “256 kinds of injection compatibility changes in the search table,” it is indicated that the two are incompatible with the use of the clinical inconvenience. This article through the compatibility of the two pharmacy, the content of different time periods and pH value, investigate the feasibility of compatibility of the two pharmacy.