本文对小鼠HepA腹水型肝癌(简称HepA,下同)细胞核与正常小鼠肝细胞核的转录活性进行了一些比较研究,发现HepA细胞核的转录活性比正常肝细胞核升高约80%,其中,依赖于DNA的RNA聚合酶Ⅱ(简称RPase Ⅱ,下同)的活性比RPase Ⅰ有更显著的增加,转录活性的升高以起始速率的增强为主。两种细胞核内的RPase Ⅱ的性质有明显的差别。 In this study, we compared the transcriptional activities of the HepA ascitic hepatocellular carcinoma (HepA, the same below) nuclei and the normal mouse liver nuclei, and found that the transcriptional activity of the HepA nuclei was approximately 80% higher than that of the normal liver nuclei. The activity of RNA polymerase II (abbreviated as RPase II, hereinafter abbreviated) in DNA is more significantly increased than that of RPase I, and the increase in transcriptional activity is dominated by the increase in the initial rate. There are significant differences in the nature of RPase II within the two cell nuclei.