幽门螺旋杆菌(Helicobacter pylori,Hp)是一种革兰氏阴性杆菌,主要生存在人体强酸性环境的胃黏膜中[1]。幽门螺旋杆菌的分布很广,其在世界范围的人群平均感染率超过50%,发展中国家的感染率高于发达国家[2]。虽然绝大多数感染幽门螺旋杆菌的人并没有明确的临床症状,但幽门螺旋杆菌是急慢性胃炎、消化性溃疡、胃淋巴瘤以及 Helicobacter pylori (Hp) is a Gram-negative bacilli that mainly lives in the gastric mucosa of the human body in a strongly acidic environment [1]. Helicobacter pylori is widely distributed, with an average prevalence of more than 50% in people worldwide, and in developing countries higher than in developed countries. [2] Although the vast majority of people infected with H. pylori do not have clear clinical symptoms, H. pylori is acute and chronic gastritis, peptic ulcer, gastric lymphoma and