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作者报告90例获得性免疫缺陷综合征(AIDS)患者,18例有CNS 受累,其中12例为中枢神经系统弓形体病。6例为海地人,其余6例中3例静脉滥用药物、1例与海地人同性恋、1例同性恋,另外1例未发现致病因素。6例在全身症状前、2例在全身症状同时、4例在全身症状后出现CNS 受累症状。9例弓形体血清学检查阳性。2例反复检查发现弓形体,效价持续性增高。3例血Sabin-Feldman染剂试验效价>1∶6400(正常<1∶100),2例CSF效价增高。7例血清toxo-elisa 弓形体抗体酶联免疫吸收试验异常,其中4例CSF 中2例为阴性。6例血清免疫荧光试验异常,其中4例CSF 中2例异常。CT 扫描11例显示分散性病变,其中8例表现两处以
The authors reported 90 patients with Acquired Immunodeficiency Syndrome (AIDS) and 18 had CNS involvement, 12 of whom were CNS Toxoplasmosis. Six were Haitians and the other six were intravenous drug abuse, one was homosexual with Haitian, one was homosexual, and the other one was not found to be causative. Six patients had systemic symptoms, two had systemic symptoms at the same time, and four had symptoms of CNS involvement after systemic symptoms. Toxoplasma serology was positive in 9 cases. Toxoplasma gondii were found in 2 cases and the titer was continuously increased. Three cases of Sabin-Feldman dye test titer> 1: 6400 (normal <1: 100), 2 cases of CSF titer increased. Seven cases of toxo-elisa Toxoplasma antibody ELISA abnormalities, of which 4 cases of CSF 2 were negative. Six cases of abnormal serum immunofluorescence test, of which 4 cases of CSF abnormalities in 2 cases. 11 cases showed diffuse lesions on CT scan, of which 8 cases showed two