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目的探讨TCT与HPV检测在宫颈疾病筛查中的应用价值。方法采取回顾性方法对我院2005年1月～2013年1月间195例诊断为宫颈疾病患者的TCT和HPV进行分析。结果通过两种项指标的测定,检测HPV阳性患者177例,HPV阳性率为90.7%;检测TCT阳性患者137例,TCT阳性率为70.3%。HPV阳性率与TCT阳性率比较具有明显的差异(X2=7.23,P<0.05),统计学有意义。HPV对判断病变程度更加具有优越性,CINⅠ-Ⅲ病变HPV阳性率均明显的高于TCT阳性率,组间的数据比较具有明显的差异(X2=7.46,X2=7.17,X2=6.27,P<0.05),统计学有意义。结论在宫颈疾病的筛查中检测HPV的敏感性优于TCT,临床中可以选取检测HPV进行宫颈疾病的筛查,提高临床应用价值。
Objective To investigate the value of TCT and HPV in the screening of cervical diseases. Methods A retrospective analysis of our hospital from January 2005 to January 2013 195 cases of patients diagnosed as cervical disease TCT and HPV were analyzed. Results 177 samples with HPV positive were detected by the two items, and the positive rate of HPV was 90.7%. The positive rate of TCT in 137 TCT positive patients was 70.3%. The positive rate of HPV and TCT positive rate was significantly different (X2 = 7.23, P <0.05), statistically significant. HPV was more superior in judging the degree of lesion. The positive rate of HPV in CINⅠ-Ⅲ was significantly higher than that in TCT (X2 = 7.46, X2 = 7.17, X2 = 6.27, P < 0.05), statistically significant. Conclusion The detection of HPV in cervical disease screening is better than TCT in the screening of cervical disease screening, HPV testing can be selected for cervical screening of cervical disease, improve clinical value.