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目的:探究中药联合小剂量美罗华治疗成人慢性难治性免疫性血小板减少症(ITP)的效果。方法:选取广东省中医院收治的成人慢性难治性ITP患者6例,采取中药联合小剂量美罗华进行治疗,观察治疗后的效果。结果:6例患者均完成治疗,总有效率为100%,无出血倾向,血小板较治疗前升高。2例患者发生静脉输注相关事件,经减慢滴注速度及对症处理后症状改善并坚持输注完毕;6例患者至今均无复发。结论:中药联合小剂量美罗华治疗成人慢性难治性ITP的效果较好。
Objective: To explore the effect of traditional Chinese medicine combined with low-dose rituximab in the treatment of chronic refractory immune thrombocytopenia (ITP) in adults. Methods: Six adult patients with chronic refractory ITP admitted to Guangdong Provincial Hospital of Traditional Chinese Medicine were selected and treated with traditional Chinese medicine combined with low dose of Rituximab to observe the effect after treatment. Results: All 6 patients completed the treatment, with a total effective rate of 100%, no bleeding tendency, and platelets increased compared with those before treatment. Two patients had an IV infusion-related event. The infusion rate was slowed down and symptoms were improved after symptomatic treatment and infusion was completed. No recurrence occurred in 6 patients so far. Conclusion: Chinese medicine combined with low-dose rituximab treatment of adult chronic refractory ITP better.