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目的利用心脑血管联合造影分析冠状动脉与弓上动脉(包括颈内动脉颅外段及颅内段、椎动脉颅外段及颅内段)病变的相关性。方法对怀疑冠状动脉粥样硬化性心脏病(coronary artery disease,CAD)且颈动脉彩超或经颅多普勒或脑血管增强CT检查提示存在弓上动脉狭窄的180例患者进行同期或分期心脑血管联合造影检查,根据冠状动脉造影(coronary angiography,CAG)结果,将患者分为两组:1)非CAD组:冠状动脉狭窄<50%;2)CAD组:冠状动脉狭窄≥50%,分析冠状动脉病变情况与弓上动脉各段病变的关系,用Logistic回归模型评价二者的相关性。结果颈动脉颅内段、颈动脉颅外段及椎动脉颅内段狭窄在CAD与非CAD组差异均无统计学意义(P=0.166、0.146、0.128);椎动脉颅外段狭窄在CAD组发病率明显高于非CAD组(P=0.010)。结论冠状动脉病变可能与椎动脉颅外段病变密切相关。
Objective To analyze the correlation between coronary arteries and the superior arteries (including the extracranial and intracranial segments of the internal carotid artery, the extracranial segments of the vertebral artery and intracranial segments) by means of cardiovascular and cerebrovascular imaging. Methods 180 patients with coronary artery disease (CAD) who underwent carotid ultrasonography or transcranial Doppler or cerebrovascular contrast enhanced CT scan were found to have synchronous or episodic cardiocerebellar According to coronary angiography (CAG) results, the patients were divided into two groups: 1) non-CAD group: less than 50% coronary stenosis; 2) CAD group: ≥50% coronary stenosis, Coronary artery lesions and the various segments of the artery on the relationship between the disease, Logistic regression model to evaluate the correlation between the two. Results There was no significant difference in intracranial segments of carotid artery, extracranial carotid segment and intracranial segments of vertebral artery between CAD and non-CAD groups (P = 0.166,0.146,0.128) The incidence was significantly higher than the non-CAD group (P = 0.010). Conclusion Coronary artery lesions may be closely related to the extracranial lesions of the vertebral artery.