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目的:探讨应用3D打印技术制作胎儿主动脉弓及其分支异常模型的可行性与应用价值。方法:选择2019年3月至2020年7月在武汉大学人民医院接受胎儿心脏超声检查的主动脉弓及其分支异常胎儿11例，采集常规超声心动图及时间-空间相关成像(spatio-temporal image correlation，STIC)容积图像。采用Mimics软件对STIC容积数据进行后处理建模，获取胎儿大血管及其分支的三维重建图像标准镶嵌语言(standard tessellation language，STL)格式文件，输出文件至3D打印机，打印胎儿大血管及其分支3D模型。与常规超声对照研究，分析各型胎儿主动脉弓及其分支异常3D打印模型的特征表现及应用价值。结果:11例胎儿均成功进行建模并打印出大血管及其分支模型。3D打印模型在显示主动脉弓及其分支异常方面具有其自身的优势，可以提供高质量成像的解剖学细节，直观显示大血管位置、分支起源及走行，能较好地显示血管环的空间关系。结论:应用3D打印技术制作胎儿主动脉弓及其分支异常模型切实可行，3D打印模型能直观展示其特征性改变，可为产前阶段准确判断血管环类型提供一定参考依据。“,”Objective:To explore the feasibility and application value of three dimensional (3D) printing technology in creating models of abnormal fetal aortic arch and its branches.Methods:Eleven cases of abnormal fetuses confirmed fetal aortic arch and its branches anomalies from March 2019 to July 2020 in Renmin Hospital of Wuhan University were prospectively enrolled. All the fetuses underwent two dimensional(2D) echocardiography and spatio-temporal image correlation (STIC) technology examination. The 3D volume images of fetal heart were post-processed by Mimics software to create images of the great vessels and their branches in standard tessellation language format (STL) file. The STL file was output to the 3D printer and the 3D printing models of fetal great vessels and their branches were obtained. Compared with conventional ultrasound, the characteristics and application value of 3D printed models of abnormal fetal aortic arch and its branches were analyzed.Results:Eleven fetuses were successfully modeled and printed out large blood vessels and their branch models. The 3D printing model had its own advantages in displaying large blood vessels and their branch abnormalities. It could provide high quality imaging anatomical details and visualize great vessels origin, branch and position and can better display vascular ring spatial relations.Conclusions:It is feasible to use 3D printing technology to make the fetal aortic arch and its branch abnormal model. The 3D printing model can directly display its characteristic changes and provide a certain reference basis for accurately determining the type of vascular ring in the prenatal stage.