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80年代出现的氟喹诺酮类抗菌药是一群具有4-吡啶酮-3-羧基和氟原子共同结构的全化学合成化合物,其抗菌谱比第一、二代喹诺酮类抗菌药(如萘啶酸、吡哌酸)广,抗菌作用也比第一、二代喹诺酮类抗菌药强。其临床特点为:
The fluoroquinolone antibacterials that appeared in the 1980s are a group of all chemically synthesized compounds that have a common structure of 4-pyridinone-3-carboxyl and fluorine atoms. Their antibacterial spectrum is better than that of the first and second generation quinolones (such as nalidixic acid, The antibacterial effect of pipemidic acid is stronger than that of the first and second generation quinolones. Its clinical features are: