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目的探讨妊娠期甲状腺功能减低与妊娠结局之间的相互关系,以提高妊娠结局并保护胎儿安全。方法对2014年1月-2015年1月在该院就诊的3 500例孕产妇资料进行回顾性分析,按照随机双盲对照的原则从中抽取100例妊娠合并甲状腺功能减低的患者为观察组,同时抽取100例正常妊娠妇女为对照组。比较两组妊娠结局以及对胎儿的影响。结果观察组不良妊娠结局的发生率高于对照组,两组比较,差异有统计学意义(P<0.05)。结论妊娠合并甲状腺功能减低患者各种并发症的发生几率明显升高。在妊娠期应及时复查甲状腺功能,一经发现要及时诊断和治疗,减少不良事件的发生几率。
Objective To explore the relationship between the hypothyroidism during pregnancy and pregnancy outcome in order to improve pregnancy outcome and protect the safety of the fetus. Methods A retrospective analysis was conducted on 3 500 cases of pregnant women attending the hospital from January 2014 to January 2015. 100 cases of pregnant women with hypothyroidism were selected as the observation group according to the principle of randomized double-blind control. At the same time, 100 normal pregnant women were taken as the control group. The pregnancy outcomes and the effects on the fetus in both groups were compared. Results The incidence of adverse pregnancy outcomes in the observation group was higher than that in the control group. There was significant difference between the two groups (P <0.05). Conclusion The incidence of complications in pregnancy with hypothyroidism is significantly increased. In pregnancy should be promptly reviewed thyroid function, once found to be timely diagnosis and treatment, reduce the incidence of adverse events.