一.一般临床资料:21例中男性13例,女8例,最大年龄74岁,最小年龄21岁。 (一)顽固性腹水的判定标准:21例病人均为我院消化科诊断的失代偿期门脉性肝硬化腹水病人,并已排除癌性腹水。顽固性腹水的判定是根据Vein和Arroyo的肝硬化腹水分期标准并参照Balaus的肝硬化腹水分期。主要临床指标是1.大量腹水并不同程度的浮肿,病程超过三个月;2.血钠低或/及血钾高;3.尿钾低;4.对水钠不耐受;5.对利尿剂(包括噻嗪类和速尿)疗效差。 First, the general clinical data: 21 cases of 13 males and 8 females, the maximum age of 74 years, the minimum age of 21 years. (A) of refractory ascites criteria: 21 patients were diagnosed in our hospital gastroenterology of decompensated portal cirrhosis ascites patients, and have ruled out cancerous ascites. Refractory ascites was determined on the basis of the cirrhosis ascites staging criteria of Vein and Arroyo and with reference to Balaus cirrhosis ascites staging. The main clinical indicators are 1. A large number of ascites and varying degrees of edema, duration of more than three months; 2. Low serum sodium or / and high serum potassium; 3. Urinary potassium is low; 4. To sodium and water intolerance; Diuretics (including thiazides and furosemide) have poor efficacy.