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抗肿瘤药物治疗中的“救援疗法”是根据阻断DNA合成的作用环节的原理设计的一种抗肿瘤化疗法,即在肿瘤早期,在肿瘤区域动脉注射或输注氨甲蝶呤,并加用肌注甲酰四氢叶酸救援,可使肿瘤局部受药物作用较多,而其吸收毒性又可被甲酰四氢叶酸所对抗,这样可加大氨甲蝶呤用量,提高疗效、降低全身毒性。这种疗法适用于肢体、盆腔、肝、头颈部癌瘤。 “半身化疗”是根据氮芥进入人体后迅速解离,
The “rescue therapy” in anti-cancer drug therapy is an anti-tumor therapy designed according to the principle of blocking the action of DNA synthesis. In the early stage of tumor, arterial infusion or infusion of methotrexate is performed in the tumor area. With the addition of intramuscular injection of formyltetrahydrofolate, the tumor can be locally treated with more drugs, and its absorption toxicity can be counteracted by formyl tetrahydrofolate, which increases the dose of methotrexate and improves the efficacy. Reduce systemic toxicity. This therapy is suitable for limb, pelvic, liver, head and neck cancers. “Half-body chemotherapy” is based on the rapid disassociation of nitrogen mustard after it enters the body.