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本文为进一步探讨妊娠性高血压综合征（妊高征）的发病机理，寻求最佳治疗药物，采用取抗体夹心酶联免疫（ELISA）法测定34例妊高征患者血管性假血友病因子（vWF）及检溶二聚体（D－Dm）的血浆水平。结果发现妊高征患者vWF、D－Dm的血浆水平明显高于正常妊娠组（轻度p＜0.05，中、重度p＜0.01）.并随病情加重呈升高趋势。证实妊高征的发生与发展与血管内皮细胞功能异常和损伤及高粘、高凝血状态有关．对妊高征的诊断、治疗具有重要的指导意义。
In order to further explore the pathogenesis of pregnancy-induced hypertension syndrome (PIH) and seek the best therapeutic drug, take the antibody sandwich enzyme-linked immunosorbent assay (ELISA) 34 cases of PIH patients von Willebrand factor (VWF) and soluble dimers (D-Dm). The results showed that the plasma levels of vWF and D-Dm in patients with PIH were significantly higher than those in normal pregnancy (mild p <0.05, moderate and severe p <0.01), and increased with the severity of the disease. Confirmed the occurrence and development of pregnancy-induced hypertension and vascular endothelial dysfunction and injury and high viscosity, high blood coagulation state. The diagnosis and treatment of PIH have important guiding significance.