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目的探讨鼓室内注入0.3%氧氟沙星滴耳液配合泼尼松龙治疗分泌性中耳炎(SOM)的效果。方法对140例(160耳)SOM患者(治疗组)行鼓膜穿刺,并向鼓室内注射0.3%氧氟沙星滴耳液和泼尼松龙;对照组144例(160耳)鼓室内注射泼尼松龙。随访2个月,对两组的总有效率和治疗次数进行比较。结果治疗组总有效率为97.5%,对照组总有效率为90.0%,两组比较,χ2=7.68,P<0.01;两组治疗次数比较,χ2=104.532,P<0.01。结论 0.3%氧氟沙星滴耳液配合泼尼松龙鼓室内注射对SOM患者有明显疗效。
Objective To investigate the effect of intrathecal injection of 0.3% ofloxacin ear drops in combination with prednisolone in the treatment of secretory otitis media (SOM). Methods One hundred and sixty ears of patients with SOM (treatment group) underwent tympanic membrane puncture and received 0.3% ofloxacin ear drops and prednisolone into the tympanic cavity. In the control group, 144 cases (160 ears) received intratympanic injection Nisong dragon. The follow-up period was 2 months, the total efficiency of the two groups and the number of treatment were compared. Results The total effective rate was 97.5% in the treatment group and 90.0% in the control group. Χ2 = 7.68, P <0.01. The comparison of the two groups was χ2 = 104.532, P <0.01. Conclusion 0.3% ofloxacin ear drops with prednisone dragons intravenous injection of SOM patients with significant effect.