论文部分内容阅读
目的：评价壳聚糖季铵盐硅凝胶抑制瘢痕形成的临床疗效及不良反应。方法在郑州欣奕中医院与欣奕除疤，挑选200例各类新伤口患者（创面愈合，已无渗液），分为两组，试验组：创面正常治疗护理，愈合后使用壳聚糖季铵盐硅凝胶，对照组：创面正常治疗护理，愈合后不使用任何产品，观察3个月，通过对瘢痕类型、瘢痕颜色、瘢痕隆起的高度、瘢痕硬度、瘢痕瘙痒、触痛这6个方面分别进行评分，综合评定其疗效及安全性同时随访患者治疗结束后的副作用，随访至1年。结果试验组平均总评分为1.52，对照组平均总评分为3.18，壳聚糖季铵盐硅凝胶抑制瘢痕形成的效果显著，与对照组相比，平均总评分降低了52.20%，最终形成的瘢痕更接近皮肤，且均未发现任何毒副作用。结论与对照组相比，壳聚糖季铵盐硅凝胶抑制瘢痕形成效果明显，安全性高，使用方便，具有临床推广价值。“,”Objective To evaluate the clinical efficacy of a shell SQASC inhibit scar formation and adverse reactions. Methods In Zhengzhou Xin Yi hospital choose 200 cases of patients with all kinds of form new wound dermis (the wound has no drainage), divided into two groups, SQASC with normal treatment and normal treatment. simple observation 3 months, based on the type of scar, scar color, the height of the scar uplift, scar hardness, scar itching, tenderness score with these six aspects respectively, comprehensive evaluation of the efficacy and safety at the same time follow-up of patients after the treatment, the side effects of follow-up to one year. Results SQASC average 1.52overall, conventional treatment average 3.18 overall, SQASC inhibited the formation of scar significantly, compared with the control group, the average total score decreased by 52.20%, the final formation of the scar closer to the skin. No toxic side effects were found. Conclusion Compared with conventional treatment, obvious effects of SQASC inhibit scar formation, high safety, easy to use, and has clinical value.