目的分析原发性甲状腺功能减退症 (简称甲减 )的误诊原因 ,探讨诊治体会。方法回顾 10 5例临床资料并结合文献进行分析。结果共误诊 48例 ,占 44.7%。结论甲减的临床表现多样 ,极易造成误诊 ,提高诊断率的关键在于想到本病的存在 ,结合临床表现进行必要的甲状腺功能检查 Objective To analyze the causes of misdiagnosis of primary hypothyroidism (Hypothyroidism) and to explore the experience of diagnosis and treatment. Methods The clinical data of 105 cases were reviewed and analyzed according to the literature. Results A total of 48 cases were misdiagnosed, accounting for 44.7%. Conclusion The clinical manifestations of hypothyroidism varied, easily lead to misdiagnosis, the key to improve the diagnosis rate is the thought of the existence of this disease, combined with clinical manifestations of the necessary thyroid function tests