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目的对三维全方位肿瘤立体放疗(3D-CRT)联合化疗与单纯放疗治疗食管癌老年患者的疗效及安全性进行对比以及探讨。方法将110例老年食管癌患者根据入院前后顺序随机分为观察组与参照组,每组55例。观察组采用3D-CRT联合化疗,参照组采用单纯放疗治疗方法。对两组的治疗效果进行对比分析。结果观察组患者治疗总有效率为94.55%,明显高于参照组的81.82%,差异有统计学意义(P<0.05)。结论对老年食管癌患者进行3D-CRT联合化疗的治疗效果明显高于单纯放疗治疗效果,值得推广。
Objective To compare and discuss the efficacy and safety of three-dimensional radiotherapy (3D-CRT) combined with chemotherapy and radiotherapy alone in elderly patients with esophageal cancer. Methods A total of 110 elderly patients with esophageal cancer were randomly divided into observation group and reference group according to the order of admission, with 55 cases in each group. Observation group using 3D-CRT combined with chemotherapy, the reference group using a simple radiotherapy treatment. The two groups of treatment were compared. Results The total effective rate of the observation group was 94.55%, which was significantly higher than that of the reference group (81.82%), the difference was statistically significant (P <0.05). Conclusion The treatment of elderly patients with esophageal cancer by 3D-CRT combined with chemotherapy was significantly higher than the effect of radiotherapy alone, it is worth promoting.