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目的:观察瘢痕子宫中期妊娠引产中应用米非司酮联合水囊的安全性与有效性。方法:选择妊娠18~24周有剖宫产史的孕妇60例,B超提示子宫瘢痕愈合良好,将60例孕妇随机分为观察组和对照组,每组各30例。其中,观察组30例患者采用米非司酮联合自制水囊引产方法;对照组采用自制水囊引产方法。结果:观察组置入水囊到宫缩发动时间(17.05±6.61)h、总产程(13.67±4.52)h与对照组[(25.05±7.30)h、(18.75±5.23)h]比较,差异有高度统计学意义(P<0.01);观察组胎盘胎膜残留率(16.67%)、产后出血量(62.38±32.04)ml与对照组[(26.67%)、(75.12±33.25)ml]比较,差异无统计学意义(P>0.05);两组均无子宫破裂及软产道裂伤。结论:米非司酮联合自制水囊终止瘢痕子宫中期妊娠是安全有效的。
Objective: To observe the safety and efficacy of mifepristone combined with water balloon in inducing labor during the second trimester pregnancy of scar uterus. Methods: Sixty pregnant women with history of cesarean section were selected from 18 to 24 weeks gestation. B-ultrasound showed good healing of uterine scar. Sixty pregnant women were randomly divided into observation group and control group, with 30 cases in each group. Among them, the observation group of 30 patients with mifepristone combined with homemade water abortion method; control group using self-made water abortion method. Results: Compared with the control group [(25.05 ± 7.30) h, (18.75 ± 5.23) h], the difference between the observation group and the control group (17.05 ± 6.61) h and 13.67 ± 4.52 h (16.67%), postpartum hemorrhage (62.38 ± 32.04) ml in control group [(26.67%), (75.12 ± 33.25) ml], the difference was statistically significant (P <0.01) No statistical significance (P> 0.05); no uterine rupture and soft birth canal laceration in both groups. Conclusion: It is safe and effective to use mifepristone combined with homemade balloon to terminate scar pregnancy.