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目的探讨血清白蛋白、非结合胆红素检测在新生儿黄疸中的应用价值及临床分析。方法 2011年7月至2012年7月许昌市人民医院诊治的60例新生儿黄疸患儿,根据不同的严重程度和病因,对其非结合胆红素、非结合胆红素/白蛋白、总胆红素,以及β2微球蛋白水平,进行观察和比较。结果伴随病变程度地加重和不同病因(梗阻性黄疸、溶血性黄疸以及感染性黄疸),非结合胆红素、非结合胆红素/白蛋白、总胆红素以及β2微球蛋白水平均依次明显升高,差异有统计学意义(P<0.05)。结论对于新生儿黄疸患儿根据病变严重程度和病因给予针对性治疗,有利于患儿的预后。
Objective To investigate the value and clinical analysis of serum albumin and unconjugated bilirubin in neonatal jaundice. Methods From July 2011 to July 2012, 60 cases of neonatal jaundice diagnosed and treated in Xuchang People’s Hospital were divided into two groups according to different severity and etiology. Their non-conjugated bilirubin, unconjugated bilirubin / albumin, Bilirubin, and β2 microglobulin levels were observed and compared. Results With the severity of pathological changes and different causes (obstructive jaundice, hemolytic jaundice and infectious jaundice), unconjugated bilirubin, unconjugated bilirubin / albumin, total bilirubin and β2 microglobulin levels in turn Was significantly higher, the difference was statistically significant (P <0.05). Conclusion Neonatal jaundice in children according to the severity of the disease and cause of targeted treatment, is conducive to the prognosis of children.