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1例22岁女性患者因月经不调及阴道炎给予口服黄体酮40 mg,3次/d;甲睾酮5 mg,1次/d;硝呋太尔0.4 g,3次/d;裸花紫珠片2片,3次/d。3 d后患者出现全身皮肤及巩膜黄染,尿色呈浓茶色。实验室检查:红细胞3.02×1012/L,网织红细胞0.034,总胆红素141.3μmol/L,直接胆红素9.7μmol/L,间接胆红素131.6μmol/L。遂停用黄体酮、甲睾酮及硝呋太尔,继续使用裸花紫珠片,并给予多种药物治疗。患者黄疸逐渐消退,尿色逐渐恢复正常。停药后第11天黄染症状完全消退,实验室检查:红细胞2.94×1012/L,网织红细胞0.021;总胆红素15.2μmol/L,直接胆红素5.8μmol/L,间接胆红素9.4μmol/L。
One 22-year-old female patient was given oral progesterone 40 mg 3 times daily for irregular menstruation and vaginitis; methyltestosterone 5 mg once daily; nifuratel 0.4 g three times daily; Beads 2, 3 times / d. After 3 days, the patient developed yellowish skin and sclera, dark brown urine color. Laboratory tests: red blood cells 3.02 × 1012 / L, reticulocytes 0.034, total bilirubin 141.3μmol / L, direct bilirubin 9.7μmol / L, indirect bilirubin 131.6μmol / L. Then stop the use of progesterone, methyltestosterone and nifuratel, continue to use the naked flower Violet tablets, and given a variety of drug treatment. Jaundice patients gradually subsided, urine gradually returned to normal. On the 11th day after treatment, the symptoms of yellow dye completely subsided. Laboratory tests showed that the number of erythrocytes was 2.94 × 1012 / L, the reticulocyte was 0.021, the total bilirubin was 15.2μmol / L, the direct bilirubin was 5.8μmol / L, the indirect bilirubin 9.4 μmol / L.