论文部分内容阅读
目的 观察脑梗死急性期患者血清中血管细胞粘附分子 - 1(VCAM- 1)的含量变化 ,并探讨其临床意义。方法 采用双抗体夹心 EL ISA法测定血清中可溶性 VCAM- 1的含量。结果 脑梗死患者急性期血清可溶性VCAM- 1含量明显高于正常对照组 (P<0 .0 1)。含量与病灶大小呈正相关 (P<0 .0 5 )。结论 测定血清 VCAM- 1含量有助于脑梗死的早期诊断、判断病灶大小及估计预后。
Objective To observe the changes of serum vascular cell adhesion molecule - 1 (VCAM - 1) in patients with acute cerebral infarction and to explore the clinical significance. Methods Serum soluble VCAM-1 levels were measured by double-antibody sandwich ELISA. Results The serum level of soluble VCAM-1 in patients with acute cerebral infarction was significantly higher than that in the normal control group (P <0.01). The content was positively correlated with the size of the lesion (P <0.05). Conclusions The determination of serum VCAM-1 content is helpful for the early diagnosis of cerebral infarction, judging the size of the lesion and estimating the prognosis.