目的:评估儿童序贯器官衰竭评分(pSOFA)预测儿童脓毒症严重程度和预后的临床价值。方法:回顾分析2014年2月至2015年1月收入上海交通大学医学院附属上海儿童医学中心重症医学科诊断为脓毒症和严重脓毒症的患儿资料，计算入科第1天pSOFA、小儿危重病例评分(PCIS)、第三代小儿死亡危险评分(PRISM Ⅲ)和儿童多器官功能障碍评分(P-MODS)。Spearman相关分析评估pSOFA与PCIS、PRISM Ⅲ和P-MODS评分的相关性以及与器官功能障碍、机械通气时间的相关性；受试者工作特征(ROC)曲线下面积(AUC)法比较pSOFA和PCIS、PRISM Ⅲ、P-MODS评分对儿童脓毒症严重程度和住院期间预后的预测价值。结果:共纳入患儿91例，其中住院期间存活58例，死亡33例。相关性分析显示pSOFA与P-MODS评分具有最好的相关性(n R＝0.709，n P6分(敏感性93.9%，特异性77.6%)。n 结论:pSOFA较PCIS、PRISM Ⅲ和P-MODS评分可更好地预测儿童脓毒症严重程度和住院期间的预后。因此，纳入pSOFA评分有助于儿童脓毒症的诊断和治疗。“,”Objective:To evaluate the clinical value of pediatrics sequential organ failure assessment(pSOFA)score in predicting the severity and outcome of sepsis in children.Methods:Data of children with sepsis and severe sepsis were collected from February 2014 to January 2015 in the pediatric intensive care unit, Shanghai Children′s Medical Center Affiliated to Shanghai Jiao Tong University School of Medicine.Scores of pSOFA, pediatric critical illness score(PCIS), pediatric risk of mortality Ⅲ(PRISM Ⅲ), and pediatric multiple organ dysfunction score(P-MODS) were collected on the first day of admission.Spearman correlation analysis was used to analyze the correlation among the pSOFA, PCIS, PRISM Ⅲ, P-MODS, meanwhile the correlation between the scores and the organ dysfunction as well as the duration of mechanical ventilation.In addition, receiver operating characteristic curve (ROC) was used to compare the predictive value of pSOFA and PCIS, PRISM Ⅲ, P-MODS in predicting the severity and prognosis of sepsis in children.Results:Ninty-one patients were collected in this study, including 58 survived cases and 33 died cases.There was the best correlation between pSOFA and P-MODS(n R=0.709, n P6 points(sensitivity 93.9%, specificity 77.6%).n Conclusion:pSOFA is better than PCIS, PRISM Ⅲ and P-MODS score in predicting the severity and outcome of sepsis in children.Therefore, pSOFA is useful to the diagnosis and treatment of children sepsis.