随着检查手段的进步,对脑转移瘤的检出率提高了,而确诊率并未提高。现在还不能说明脑转移瘤的单发病灶要比多发的恶性度低或病程短。单发还是多发不仅与其来源有关,而且与血脑屏障(BBB)的结构,瘤细胞的特性,子瘤血管的生成等因素密切相关。本文综述了脑转移瘤血管生成的一些重要因素、MR的表现及相互关系,以期进一步探讨其发生机制,提高确诊率。 With the improvement of examination methods, the detection rate of brain metastases increased, but the diagnosis rate did not increase. It is not yet clear that solitary lesions of brain metastases are less frequent or have a shorter duration than multiple malignances. Whether single or multiple is related not only to its source, but also to the structure of the blood-brain barrier (BBB), the characteristics of the tumor cells and the generation of the tumorous blood vessels. This article reviews some important factors of angiogenesis in brain metastases, the manifestation and correlation of MR, in order to further explore its mechanism and improve the diagnosis rate.