肥胖的发病率逐年攀升,已成为全球主要公共健康问题。肥胖是高血压发生发展的最重要的危险因素之一。Framingham心脏研究显示,78%的男性高血压及64%的女性高血压与超重及肥胖相关,最近的数据更指出,超过85%的高血压与体重指数(BMI)大于25kg/m~2有关。因此,肥胖相关性高血压已经成为临床工作中的常见问题,本文对这一类型高血压的发病机制作一综述。 The rising incidence of obesity has become a major public health problem worldwide. Obesity is one of the most important risk factors for the development of hypertension. Framingham Heart Study shows that 78% of men with hypertension and 64% of women with hypertension are overweight and obese. More recent data indicate that more than 85% of hypertension is associated with body mass index (BMI) greater than 25kg / m2. Therefore, obesity-related hypertension has become a common problem in clinical work, this article reviews the pathogenesis of this type of hypertension.