目的　研究血浆置换患者人群中经输血传播ＴＴ 病毒的感染状况及临床意义。方法用聚合酶链反应（ＰＣＲ） 方法检测４５ 例血浆置换患者和慢性肝炎患者的ＴＴ病毒（ＴＴＶ）感染情况，分析ＴＴＶ 感染的致病力。结果　ＴＴＶ 在４５ 例血浆置换患者中的感染率为１５ ．６ ％ （７／４５） ，在８７例慢性肝炎患者中的感染率３ ．４ ％ （３／８７） ，经统计学处理，两组感染率比较差异有显著性（χ２ ＝４ ．６０ ，Ｐ＜ ０ ．０５） 。７ 例ＴＴＶ 阳性患者中，６ 例有输血史。且ＴＴＶ 阳性和ＴＴＶ 阴性两组之间病死率差异无统计学意义。结论　输血、血浆在传播ＴＴＶ 感染有重要意义，ＴＴＶ 是否导致或促进重型肝炎肝衰竭的因素，有待深入研究 Objective To study the infection status of transfusion-transmitted TT virus in patients with plasma exchange and its clinical significance. Methods TTV infection was detected in 45 patients with plasmapheresis and chronic hepatitis by polymerase chain reaction (PCR), and the pathogenicity of TTV infection was analyzed. Results The infection rate of TTV in 45 patients with plasma exchange was 15. 6% (7/45), infection rate in 87 patients with chronic hepatitis 3. 4% (3/87). After statistical analysis, the infection rates of the two groups were significantly different (χ2 = 4.60, P <0.05). Of the 7 TTV positive patients, 6 had a history of blood transfusions. There was no significant difference in the case fatality rate between TTV positive and TTV negative. Conclusion Blood transfusions, plasma transmission of TTV infection is of great significance, TTV whether lead to or promote the factors of severe hepatitis, liver failure needs further study