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目的为了解新泰市疫苗疑似预防接种异常反应(adverse events following immunization,AEFI)的发生特征,评价AEFI监测系统的运转状况、疫苗预防接种的安全性。方法对新泰市2013—2014年的AEFI信息管理系统收集的AEFI资料进行描述流行病学的方法进行统计分析。结果新泰市2013—2014年共报告AEFI243例,平均报告发生率为30.14/10万。报告发生率,2013年为28.20/10万,2014年为32.23/10万。平均报告发生率,农村为28.16/10万,城市为39.69/10万,男性为32.06/10万,女性为27.83/10万,0岁组报告病例数最多118例(占48.56%),百白破疫苗为65.72/10万,减毒乙脑疫苗为50.08/10万。243例中,一般反应占97.53%,异常反应占1.65%,偶合症占0.82%,5月份最多,占20.58%。结论新泰市的疫苗疑似预防接种异常反应监测系统运行正常;疫苗预防接种异常反应与许多种因素相关,不同疫苗有着不同的发生率;AEFI主要发生在较低年龄组儿童。
Objective To understand the occurrence of AEFI in Xintai City, and to evaluate the operation of AEFI monitoring system and the safety of vaccination. Methods AEFI data collected by AEFI information management system in Xintai city from 2013 to 2014 was analyzed by epidemiological method. Results A total of 243 AEFI cases were reported in Xintai City from 2013 to 2014, with an average of 30.14 / 100,000 reported. The reported incidence was 28.20 / 100,000 in 2013 and 32.23 / 100,000 in 2014. The average incidence of reports was 28.16 / lakh in rural areas, 39.69 / lakh in urban areas, 32.06 / lakh in males and 27.83 / lakh in females, and 118 cases (48.56%) were reported in 0-year-olds, 65.72 / 100,000 were broken vaccines and 50.08 / 100,000 were attenuated JE vaccine. In 243 cases, the general reaction accounted for 97.53%, abnormal reaction accounted for 1.65%, coupling accounted for 0.82%, the largest in May, accounting for 20.58%. Conclusions The surveillance system for abnormal surveillance of vaccination against suspected vaccination in Xintai City is in normal operation. Abnormal responses to vaccination are related to many factors and different vaccines have different incidence rates. AEFI mainly occurs in children of lower age group.