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目的 评估血清抗脂阿拉伯甘露糖及 38kDa抗体 (LAM 38kD IgG)检测对涂阴肺结核和肺外结核的诊断价值。方法 采用斑点免疫金渗滤法 (dotimmunogoldfiltrationassay ,DIGFA)检测5 7例涂阴肺结核 ,5 2例肺外结核 ,32例涂阳肺结核 ,2 9例肺癌患者及 33例正常人血清中LAM 38kD IgG。 结果 涂阴肺结核组LAM 38kD IgG阳性率为 73.7% ,其中痰结核菌涂 (- )培 (+ )组为84 .6 % ,涂 (- )培 (- )组为 70 .5 %。肺外结核组阳性率为 71.2 % ,涂 (+ )肺结核组阳性率 93.8% ,肺癌组假阳性率 31% ,健康组假阳性率 9.1%。结论 血清LAM 38kD IgG检测对涂阴肺结核和肺外结核有一定的辅助诊断价值
Objective To evaluate the diagnostic value of serum anti-lipid arabinose and 38 kDa IgG (LAM 38 kD IgG) in smear-negative and extra-pulmonary tuberculosis. Methods Serum LAM 38kD IgG was detected by dot immunogold filtration assay (DIGFA) in 57 cases of smear-negative pulmonary tuberculosis, 52 cases of extrapulmonary tuberculosis, 32 cases of smear-positive pulmonary tuberculosis, 29 cases of lung cancer and 33 normal persons. Results The positive rate of LAM 38kD IgG in smear negative pulmonary tuberculosis was 73.7%, of which 84.6% in smear - (+) sputum and 70.5% in smear - (-) group. The positive rate was 71.2% in extrapulmonary tuberculosis group, 93.8% in coated (+) pulmonary tuberculosis group, 31% in lung cancer group, and 9.1% in healthy group. Conclusion Serum LAM 38kD IgG can be used to diagnose smear-negative and extra-pulmonary tuberculosis