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目的 探讨小儿穿孔性阑尾炎致病菌群变化特点和抗生素的合理选用。方法 回顾性分析 2 0 0 2年 7月～ 2 0 0 3年 7月我院收治的 6 6例术中脓培养阳性的小儿穿孔性阑尾炎病例 ,男 5 2例 ,女 14例 ,平均 80 .3± 36 .4个月 ,分析致病菌群的变化、耐药性特点以及与抗生素使用的关系。结果 小儿穿孔性阑尾炎致病菌仍以大肠埃希菌和铜绿假单胞菌为主 ,但其他少见致病菌的比例上升 ,致病菌的种类与术后住院时间和静脉用抗生素的时间无显著相关性。结论 穿孔性阑尾炎致病菌谱变化不明显 ,术中脓培养对术后抗生素的选择具有指导意义。
Objective To investigate the characteristics of pathogenic bacteria in children with perforated appendicitis and rational use of antibiotics. Methods Retrospective analysis of 6 6 cases of pus culture-positive perforation appendicitis in our hospital from July 2002 to July 2003 were performed. There were 52 males and 14 females, with an average of 80. 3 ± 36.4 months, analysis of the changes of pathogenic bacteria, drug resistance characteristics and the relationship with the use of antibiotics. Results The pathogens in children with perforation appendicitis were still mainly Escherichia coli and Pseudomonas aeruginosa, but the proportion of other rare pathogens increased. The types of pathogens, postoperative hospital stay and time of intravenous antibiotics Significant correlation. Conclusion The pathogenic changes of perforation appendicitis are not obvious. The pus culture during operation has the guiding significance for the choice of postoperative antibiotics.