关于美尼尔氏病的病因、发病机理和病理生理,以往有很多学说。现在的争议主要在于:有一派人认为该病是由于内淋巴囊的原发病变引起l内耳流体动力学改变的结果,另一说认为所有的临床表现、组织病理学和超微结构的变化都可由扩张的膜迷路的微小破裂或离子交换异常来解释,离子交换异常则是由于扩张破裂的膜迷路的内淋巴流入了外淋巴致外淋巴钾离子中毒的结 There are many theories about the etiology, pathogenesis and pathophysiology of Meniere’s disease. The controversy now lies mainly in the belief that the disease is due to the primary lesion of the endolymphatic sac resulting from the hydrodynamic changes in the inner ear and that all changes in clinical manifestations, histopathology and ultrastructure Can be explained by the small rupture or ion exchange abnormalities of the expanded membranous labyrinth and the abnormal ion exchange due to the endolymphatic infiltration into the lymphatic potassium intoxication