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芥子气是双功能烃化剂,中毒后可遗留长期效应。两伊战争中伊朗芥子气中毒人群成为芥子气长期效应研究的热点。对这些伊朗患者芥子气中毒后数年的研究表明,他们都有不同程度迟发性并发症产生,以眼、皮肤和呼吸系统为主,表现为皮肤的干燥、瘙痒和色素过度沉着,眼睛的结膜炎、角膜溃疡和视力障碍,呼吸系统的慢性支气管炎、支气管扩张和肺纤维化。此外,芥子气中毒的长期效应还与肿瘤的发生、生殖毒性、血液系统、免疫系统的影响和神经精神方面症状有关。
Mustard gas is a bifunctional alkylating agent that can leave long-term effects after poisoning. The Iran-Iran Mustard Gas Poisoning People in the Iran-Iraq War Became a Hot Spot in Studying the Long-term Effect of Mustard Gas. Several years after these mustard gas poisoning in Iranian patients, studies have shown that they all have varying degrees of late complications, mainly of the eye, skin and respiratory system, manifested as dry skin, itching and hyperpigmentation, the conjunctiva of the eye Inflammation, corneal ulceration and visual impairment, chronic bronchitis of the respiratory system, bronchiectasis and pulmonary fibrosis. In addition, the long-term effects of mustard gas poisoning are also associated with tumorigenesis, reproductive toxicity, the blood system, the immune system and neuropsychiatric symptoms.