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目的:探讨雾化吸入布地奈德混悬液治疗婴幼儿轻中度喘息性疾病的临床疗效,为临床提供参考经验。方法:选取我院儿科于2012年3月-2013年3月所收治的132例住院患儿为研究对象,按照对照、双盲的原则将132例患儿随机分为对照组和观察组,每组66例。对照组患儿在常规治疗基础上雾化吸入地塞米松治疗;观察组患儿在常规治疗基础上雾化吸入布地奈德混悬液治疗。观察比较两组患者治疗前后症状变化及临床疗效。结果:观察组患儿显效率为83.33%,总有效率为98.48%,与对照组的60.61%、86.36%存在统计学差异(P<0.05);观察组患儿的喘息缓解、咳嗽缓解、哮鸣音消失和住院时间均显著少于对照组患儿,差异具有统计学意义(P<0.05)。结论:雾化吸入布地奈德混悬液治疗婴幼儿轻中度喘息性疾病临床疗效好,值得广泛推广。
Objective: To investigate the clinical efficacy of inhaled budesonide suspension for mild to moderate asthmatic diseases in infants and young children, and to provide reference for clinical practice. Methods: A total of 132 inpatients admitted to our hospital from March 2012 to March 2013 were enrolled in this study. According to the principle of control and double-blind, 132 children were randomly divided into control group and observation group. Group of 66 cases. Children in the control group were treated with atomization inhalation of dexamethasone on the basis of routine treatment. The children in the observation group were treated with inhalation of budesonide suspension on the basis of routine treatment. The changes of symptoms and clinical effects in two groups before and after treatment were observed and compared. Results: The effective rate of observation group was 83.33%, the total effective rate was 98.48%, which was significantly different from that of control group (60.61%, 86.36%, P <0.05). The observation group had wheezing relief, cough relief, The disappearance of beeps and hospitalization time were significantly less than those in the control group, the difference was statistically significant (P <0.05). Conclusion: Inhaled budesonide suspension for infants and young children with mild to moderate wheezing clinical efficacy is good, it is worth widely disseminated.