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设计了一种新型的测试挥发性物质密闭容器装置，建立了一套简便、快速、实用的挥发性物质体外致突变定量检测方法。应用平衡原理测得挥发性物质培养基／气分配系数和致突变测试容器装置中空气浓度，通过简单公式计算，即可获得培养基中受试物浓度。整个定量分析过程仅需４ｈ。挥发性物质在致突变测试容器装置内可保持特定的浓度，剂量与效应关系明确。在Ａｍｅｓ致突变测试中，对沸点低于１００℃挥发性物质，必须用容器装置才能检测致变性，沸点在１００℃以上，２００℃以下，容器装置方法仍是首选有效的检测方法。
A new type of closed container device for testing volatile materials was designed and a set of simple, rapid and practical method for quantifying the mutagenicity of volatile substances in vitro was established. Application of the principle of equilibrium measured volatiles medium / gas partition coefficient and mutagenicity test container device air concentration, calculated by a simple formula, you can get the concentration of the test medium in the medium. The entire quantitative analysis process only 4h. Volatile substances in the mutagenicity test container device can maintain a specific concentration, the dose and effect of a clear relationship. In Ames mutagenicity test, volatile substances with boiling point less than 100 ℃ must be tested by container device for denaturation. The boiling point should be above 100 ℃ and below 200 ℃. Container device method is still the first choice of effective detection method.