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目的探讨全血超敏C-反应蛋白(hsCRP)在新生儿呼吸道感染中的临床意义。方法选取在本院分娩出院后,患有呼吸道感染而重新住院的86例新生儿作为研究对象,定为观察组,另取85例健康新生儿作为对照组进行全血hsCRP定量分析。结果实验组hsCRP含量显著高于对照组,差异具有统计学意义,P<0.01。另外,实验组中的肺炎组和支气管炎组全血hsCRP的浓度也显著高于正常对照组,其分别与正常对照组比较,差异均具有统计学意义,P均<0.01。且随疾病好转而逐渐降低。结论全血hsCRP的检测在新生儿呼吸道感染中具有重要的临床意义,对新生儿感染的诊断及疗效观察具有一定的临床应用价值,值得推广应用。
Objective To investigate the clinical significance of whole blood hypersensitive C-reactive protein (hsCRP) in neonatal respiratory infection. Methods Totally 86 newborns with respiratory tract infection and hospitalization after hospital discharge were selected as the observation group and 85 healthy newborns as the control group to carry out the whole blood hsCRP quantitative analysis. Results The content of hsCRP in the experimental group was significantly higher than that in the control group, the difference was statistically significant (P <0.01). In addition, the concentrations of hsCRP in the pneumonia group and the bronchitis group in the experimental group were also significantly higher than those in the normal control group. The differences were statistically significant (P <0.01). And with the improvement of the disease and gradually reduced. Conclusion The detection of whole blood hsCRP has important clinical significance in the neonatal respiratory tract infection. It has some clinical application value in the diagnosis of neonatal infection and observation of curative effect. It is worth to be popularized and applied.