大肠多发性绒毛状腺瘤伴有恶性变的不同阶段表现者较少见,现将我们遇到的一例报告如下:男性,71岁,住院号143100。5～6年前开始大便软,不成形,偶伴粘液或少量鲜血,自认为“痔”未曾就医。近2个月以来经常腹部气胀不适,脐周隐痛,大便呈糊状,混有粘液及血性粘液,有时出现便秘腹泻交替,四肢乏力,体重明显减轻. The multiple stages of multiple villous adenomas associated with malignant transformation of the large intestine are rarer, and we now report a case report as follows: Male, 71 years old, hospital number 143100. 5 to 6 years ago began stool soft, not forming With occasional mucus or a small amount of blood, he thought he had never consulted. Abdominal flatulence and discomfort in the past 2 months, pain in the umbilical period, stool was pastey, mixed with mucus and bloody mucus, sometimes alternating constipation and diarrhea, limb weakness, body weight significantly reduced.