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目的：通过测定COPD患者的肺功能和用力呼气中期平均流速等肺功能指标，探讨其在COPD诊断及评估的应用价值。方法主要是对我院2013~2015年COPD缓解期的100例患者行基础肺功能检查和支气管舒张实验，比较第一秒呼气容积(FEV1)、用力呼气中期平均流速(FEF 25%~FEF 75%)、50%及75%肺活量位的用力呼气流速(V50、V25)等指标的阳性率。从而了解小气道功能指标在COPD诊断及评估的应用价值。结果两组比较除(CC/TLC)和Viso-V无变化外，其余各项均呈有意义改变(<0.05，<0.01)。结论小气道病变是COPD患者阻力增加的主要因素，小气道功能指标对COPD诊断及评估具有一定的敏感性及早期的诊断价值。“,”Objective By measuring pulmonary function in COPD patients and forced expiratory medium-term average lung function indexes such as flow velocity, and to explore its application value in diagnosis and assessment of COPD. Methods Mainly to our hospital from 2013 to 2015, remission of 100 cases of COPD patients based on lung function and bronchial diastolic experiment, the more volume in 1 second (FEV1) and forced expiratory medium-term average flow velocity (FEF25%~FEF75%), 50%and 75%lung capacity of forced expiratory flow rate (V50 and V25), and other indicators of positive rate. To understand the small airway function index in the diagnosis and evaluate the application value of COPD. Results Comparing the two groups except (c c T L/c) and V (iso - V, there is no change in the rest of the various significant change ( < 0.05, < 0.01). Conclusion Small airway lesions are the main factors of patients with COPD resistance increased, small airway function index to COPD diagnosis and evaluation of sensitivity and the value of early diagnosis.