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胆囊收缩素八肽（ＣＣＫ－８）对中枢神经系统的神经元有强烈的兴奋作用，它不仅对痛觉、摄食行为、内分泌、学习和记忆有重要的调节作用，还对中脑－边缘系统多巴胺（ＤＡ）能神经元的功能活动产生重要影响。腹侧中脑富含ＣＣＫ受体，主要位于ＣＣＫ－８与ＤＡ共存神经元上。?
Cholecystokinin octapeptide (CCK-8) has a strong excitatory effect on the neurons of the central nervous system. It not only plays an important role in regulating pain, feeding behavior, endocrine, learning and memory, but also modulates midbrain-limbic system dopamine (DA) can exert a significant influence on the functional activity of neurons. Ventral mesencephalon is rich in CCK receptor, mainly located in CCK-8 and DA co-existing neurons. ?