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目的分析新生儿败血症的病原学检测、药敏学试验及治疗预后,为临床治疗提供一定的参考依据。方法对该院自2012年9月-2014年9月收治的98例新生儿败血症的病原学检测、药敏试验及治疗转归进行回顾性分析。结果条件致病菌中所占比例最高的为葡萄球菌,为71.15%;药敏试验显示对红霉素、青霉素、螺旋霉素、氨苄青霉素耐药率高,对头孢噻肟钠、头孢唑啉、万古霉素、苯唑西啉钠敏感率高;经治疗后患儿治愈91例(92.86%),好转5例(5.11%),死亡2例(2.04%),总有效率为97.96%。结论针对新生儿败血症,早期的评估和诊断尤为重要。同时观察患儿用药的临床表现来调整抗生素的应用,而血培养药敏试验可为抗生素的选择提供依据,使治愈率得到有效提高。
Objective To analyze the etiological detection, drug susceptibility test and prognosis of neonatal sepsis and provide some reference for clinical treatment. Methods A retrospective analysis was made on the etiological tests, drug sensitivity tests and treatment outcomes of 98 neonates with sepsis admitted to our hospital from September 2012 to September 2014. Results The highest proportion of pathogenic bacteria was Staphylococcus aureus, which was 71.15%. The antibiotic susceptibility test showed that the drug resistance rate to erythromycin, penicillin, spiramycin and ampicillin was high, and cefotaxime sodium, cefazolin , Vancomycin and oxacillin sodium. After treatment, 91 cases (92.86%) were cured, 5 cases (5.11%) were improved, 2 cases died (2.04%), and the total effective rate was 97.96%. Conclusion For neonatal sepsis, early assessment and diagnosis are particularly important. While observing the clinical manifestations of children with medication to adjust the application of antibiotics, and blood culture susceptibility testing for the selection of antibiotics provide a basis for the cure rate has been effectively improved.