Aims: Cardiac remodeling is one of the key pathological changes that occur with cardiac injury and cardiovascular disease.Previous studies have demonstrated
Prostaglandin E2 (PGE2) is a potent lipid mediator produced by metabolism of arachidonic acid via a cascade of enzymatic processes of cyclooxygenases (COX-1 and
Adverse effects of pharmacological inhibition of cyclooxygenase (COX) in colitis patients were reported.PGD2, one of downstream product of COX, was also see
Vascular adventitial remodeling is an important pathologic process in multiple vascular diseases.Reactive oxygen species (ROS) are an important triggering f
The kinetic participation of macrophages, especially M1 to M2 transition, is critical in the healing of myocardial infarction (MI).However, the mechanisms u